Mechanism of Motion: Obeticholic acid is surely an agonist for Farnesoid X Receptor (FXR), a nuclear receptor expressed within the liver and intestine. FXR is really a important regulator of bile acid, inflammatory, fibrotic and metabolic pathways. FXR activation decreases the intracellular hepatocyte concentrations of bile acids by suppressing de https://neoglycyrol23219.develop-blog.com/37495055/detailed-notes-on-luminespib