Pentobarbital will minimize the extent or influence of nelfinavir by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch. pentobarbital will reduce the extent or outcome of vinblastine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Not known. pentobarbital will minimize the level or result of trazodone by affecting hepatic/intestina... https://andersonovzdz.wizzardsblog.com/22369016/top-guidelines-of-sodium-pentobarbital-for-dogs